Every five minutes, 50 people have been cut by snakes around the world. Four will be permanently disabled and one will die. In time after cutting, it is very important to identify the snake poison that is making its way through your system to save life and provide the best.
Most approaches to the diagnosis and treatment of snake poisoning, which ignore tropical disease, relies on antibodies. There are a number of challenges associated with antibodies, including high costs, long methods and contradictions, and nevertheless, there are strong, low cost and widely available alternatives to the antibody -based approach.
In this new research paper, which appeared ACS BiomacromoleculesWarwick researchers have shown the first evidence of the concept for a cheap and fast alternative-a glycopolymer-based ultra-violet visible (UV-VIS) test to detect the poison of the snap. They offer a version of the diagnostic examination in paper, especially detects the poison of Western Diamondback Retlesonic (Crotles Etrox).
Dr. Alex Baker, Assistant Professor of the Baker Humanitarian Chemistry Group and Assistant Professor of the Article, said: “Snake is poisonous and poisonous is difficult to detect, but it is necessary to save life. We have created a bodies that are in such a way that our bodies are raised in this way. It is a high speed and it is a high speed that imitates rumors that are high and it is a high speed in our bodies.
The Western Diamond Back Retlesk poison is ready to tie specific sugar molecules on the surface of the cells in the body, such as red blood cells and platelets. Specifically, Toxin Gallactos is linked to terminal glycan (Sugar Chains that ended in Galactose). The ban on these glycans allows the poison to interfere with the blood clotting or interfere with the immune response to disability and death.
The Croatals Etroxy for poisoning for poison, the team engineered artificial chains of diabetes -like units (glicopolymers), so as to imitate natural sugar receptors through poison proteins. Artificial sugar was associated with gold nano particles to promote the reaction and make the reaction visible, a test that changes the color when the poison is linked to the poisonous artificial sugar.
Mehdi Hizwani, the first author and former student of Dr. Baker’s research group, said: “This can be a real game changer for the implementation of the snake. The poison from other snake species does not interact with the glycon in the body. Therefore, it will show that they are capable of making a variety of poisoning.
This is the first example of diagnostic tests using sugar to detect snake poison in a rapid detection system, and is following the work of the Warwick Research Group that uses the Galcono Partical Platform to detect Covade 19.
This new test is fast, cheap, easy to store, it can be modified because sugar can be customized to identify a specific toxic, and this is an example of a bold, modern solution that is possible through the University of Warwick’s new steam connection program.
