
Credit: Love.
An international team, led by researchers at the Center for Pilgegenatics, has revealed the Microbial DNA stored in Only and Stepie Memouth, which is in the history of more than a million years. The analysis has recovered the world’s oldest microbial DNA, as well as the identification of bacteria, which has potentially caused the disease. The results have been published in Cell.
Researchers at the Cooperative Cooperation Center for Peliogentics between the Stockholm University and the Swedish Museum of Natural History analyzed microbial DNA with 483 mammoth samples, of which 440 were first arranged. Among them was Stepie Memouth, who lived about 1.1 million years ago. Using modern genomic and bio -information techniques, the team distinguished microbes who once lived alongside people who attacked their remains after death.
“Imagine holding a million -year -old ancient teeth. If I told you that it still contains artifacts of ancient germs that lived with this big? Our results leave Microbial DNA study more than a million years, and to find out how to find a newcomer, to find out.
Six microbials remained on time and space
The analysis identified six microbial groups, which are permanently affiliated with the mammoth hosts, including relatives of Actinobacillus, Pasteorella, Streptococcus, and Aerisapilotherax. Some of these germs may be disease.
For example, bacteria related to a pasteurilla identified in the study have a deep connection to a pathogen, causing fatal outbreaks to African elephants. Since African and Asian elephants are the closest relatives to the mammoth, these results raise questions as to whether Memoh can suffer from similar infections.

Credit: Love
It is noteworthy that the team formed the partial genome of Aerisapilothrix from 1.1 million -year -old Stepie Memouth, represented by the Microbial DNA affiliated with the most famous host so far. This extends the limits of what researchers can learn about the interaction between ancient hosts and their microsums.
“Since microbes are faster, getting reliable DNA data in more than a million years was like following a trail that continues to rewrite themselves. Our results show that ancient remnants can maintain more biological insights than the hosts, which can maintain a more biological insight. Thought, “
A new window in ancient environmental systems
Although DNA deficiency and limited comparative data is difficult to determine the true effects of widespread germs on health, it provides an unprecedented glimpse in the microbiomes of the extinct megafona. The results suggest that some microbial lineage spreads for hundreds of thousands of years to large geographical boundaries and evolutionary times, which, about 4,000 4,000 years ago, on the Varanjal Islands a million years ago, was spread on both wide geographical limits and evolutionary times.
“This task opens a new chapter to understand the biology of the nasty species. Not only can we study the genome of the memoirs ourselves, but now we can now start looking for the microbial communities living within them,” said a professor of evolutionary genomics at the center of Palegenitics.
More information:
Germs associated with ancient hosts have left massive, Cell (2025) DOI: 10.1016/j.cell.2025.08.003. www.cell.com/cell/fulltext/s0092-8674 (25 )00917-1
Journal Information:
Cell
Provided by Stockholm University
Reference: In ancient Memouth, the bacterial DNA (2025, September 2 September) belonged to the world’s oldest host.
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