For a long time, European colonialism is considered a disease in the United States, with leprosy, in fact, can have a huge history in the American continent. Scientists from the Institute Pasteur, CNRs, and the University of Colorado (USA) have revealed that the second generation of bacteria is recently identified as leprosy, along with various institutions in the United States and Europe. Mycobacterium laparometosisEurope has been affecting humans in the United States for at least a thousand years before the arrival of European people. These results will be published in the journal Science On May 29, 2025.
Leprosy is a neglected disease, mainly due to bacterium Mycobacterium leapryInfecting thousands of people worldwide: About 200,000 new cases of leprosy are reported every year. Though A The main reason is that, the focus of this study is focused on another species, Mycobacterium laparometosisA Mexico patient was discovered in the United States in 2008, and later in red squirrels in the British island in 2016. The Microbial Pilgeneomics laboratory scientists at the Institute Pastever, also associated with CNRs and Colorado University, along with local communities and with more than 40 scientists from the University of Colorado, and more than 40 scientists from international institutions, including archaeological and archaeological issues. Results confirm this M laparrometosis The European colonialism was already wide in North and South America, and the pathogenic provides insights about the current genetic diversity of Mycobacteria.
“This discovery changes our understanding about the history of leprosy in the United States,” said Dr. Maria Loopopolo, the first author and researcher in the laboratory of the Microbial Pilgeneomics at the Institute Pastever. “This shows that a form of the disease was already localized in the indigenous population before the Europeans arrived.”
Used modern genetic techniques to reorganize team genome M laparrometosis From ancient people found in Canada and Argentina. Despite the geographical distance of several thousand kilometers, these ancient stresses were found to be genetically close to similar periods (about 1,000 a thousand years ago). Although they belong to two separate branches in the evolutionary tree of jeans MycobacteriumThese branches are genetically close to each other than any other famous branch. This genetic proximity, combined with their geographical distance, essentially means the rapid spread of pathogenic throughout the subcontinent, possibly within only a few centuries.
Scientists also identified several new tissues, including a native branch, despite being removed from the diversity of the remaining species of 9,000 years ago, it affects humans in North America today. It is a discovery that suggests an ancient and lasting diversity in the continent, as well as a massive diversity.
In particular, analysis also shows that the tensions found in the red squirrels in the UK in 2016 are part of an American lineage that was introduced in the British islands in the 19th century, where it later spread. This discovery highlights the recent Rogen’s ability to cross the continents, possibly through human or commercial exchange.
“We are recently launching the diversity of this identified pathogenic and global movements,” said Nicholas Raskovan, the head and head of the laboratory, the laboratory and laboratory, the laboratory and laboratory head of the microbial pelvicinomics in the institute pasteur. This study allows us to speculate that animals are also known. “This study clearly illustrates how the ancient and modern DNA can rewrite the history of human pathogen and help us better understand the infectious diseases of modern infectious diseases.”
The project was carried out in close cooperation with indigenous communities, who were involved in decisions regarding the use of ancestral remnants and interpretation of the results. The ancient DNA and the rest of the material were returned at the time of the application, and the data created was shared through a moral and adaptive platform to allow data sharing to meet the specific expectations of the indigenous communities.
